A prospective study of leisure-time physical activity and risk of incident epithelial ovarian cancer: Impact by menopausal status.

ABSTRACT: Despite multiple hypotheses for a protective effect, epidemiologic findings are inconsistent regarding the association between physical activity and risk of ovarian cancer. Considering physical activity assessment at different times of life, including pre- and postmenopause, may be important for explaining these discrepancies. Therefore, we examined the risk of ovarian cancer according to total, premenopausal and postmenopausal physical activity among 85,462 women from the Nurses' Health Study and 112,679 women from the Nurses' Health Study II. Leisure-time physical activity was prospectively assessed about every 2-4 years using validated questionnaires, and characterized as metabolic equivalent task hours per week (MET-hr/week), which combines exercise duration and intensity. Multivariabl

SUBMITTER: Huang T 

PROVIDER: S-EPMC4715531 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature