Bright Lu₂ O₃ :Eu Thin-Film Scintillators for High-Resolution Radioluminescence Microscopy.

ABSTRACT: The performance of a new thin-film Lu₂ O₃ :Eu scintillator for single-cell radionuclide imaging is investigated. Imaging the metabolic properties of heterogeneous cell populations in real time is an important challenge with clinical implications. An innovative technique called radioluminescence microscopy has been developed to quantitatively and sensitively measure radionuclide uptake in single cells. The most important component of this technique is the scintillator, which converts the energy released during radioactive decay into luminescent signals. The sensitivity and spatial resolution of the imaging system depend critically on the characteristics of the scintillator, that is, the material used and its geometrical configuration. Scintillators fabricated using con

SUBMITTER: Sengupta D 

PROVIDER: S-EPMC4715786 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature