Neural responses to kindness and malevolence differ in illness and recovery in women with anorexia nervosa.

ABSTRACT: In anorexia nervosa, problems with social relationships contribute to illness, and improvements in social support are associated with recovery. Using the multiround trust game and 3T MRI, we compare neural responses in a social relationship in three groups of women: women with anorexia nervosa, women in long-term weight recovery from anorexia nervosa, and healthy comparison women. Surrogate markers related to social signals in the game were computed each round to assess whether the relationship was improving (benevolence) or deteriorating (malevolence) for each subject. Compared with healthy women, neural responses to benevolence were diminished in the precuneus and right angular gyrus in both currently-ill and weight-recovered subjects with anorexia, but neural responses to malevolence di

SUBMITTER: McAdams CJ 

PROVIDER: S-EPMC4715806 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature