Agent-Based Modeling in Systems Pharmacology.

ABSTRACT: Modeling and simulation (M&S) techniques provide a platform for knowledge integration and hypothesis testing to gain insights into biological systems that would not be possible a priori. Agent-based modeling (ABM) is an M&S technique that focuses on describing individual components rather than homogenous populations. This tutorial introduces ABM to systems pharmacologists, using relevant case studies to highlight how ABM-specific strengths have yielded success in the area of preclinical mechanistic modeling.

SUBMITTER: Cosgrove J 

PROVIDER: S-EPMC4716580 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature