Clustering of monozygotic twinning in IVF.

ABSTRACT:

Purpose

The aim of this analysis was to study whether monozygotic twinning (MZT) events occur in clusters after IVF and, if so, to explore possible explanations for this clustering.

Methods

This is a retrospective cohort study carried out in a single, large university-affiliated reproductive medicine practice. Medical records of all patients who had undergone fresh IVF cycles, resulting in a viable clinical pregnancy, from Jan 2002 to Dec 2013 were reviewed. The incidence of MZT in 6-month intervals and the association with independent risk factors such as maternal age, extended embryo culture, PGD/intracytoplasmic sperm injection (ICSI)/assisted hatching performed were analyzed.

Results

Over the 12-year study period, 25,502 fresh IVF cycles were performed, resulting

SUBMITTER: Vaughan DA 

PROVIDER: S-EPMC4717144 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature