Do people from the Jewish community prefer ancestry-based or pan-ethnic expanded carrier screening?

ABSTRACT: Ancestry-based carrier screening in the Ashkenazi Jewish population entails screening for specific autosomal recessive founder mutations, which are rarer among the general population. As it is now technically feasible to screen for many more diseases, the question arises whether this population prefers a limited ancestry-based offer or a pan-ethnic expanded carrier screening panel that goes beyond the diseases that are frequent in their own population, and is offered regardless of ancestry. An online questionnaire was completed by 145 individuals from the Dutch Jewish community (≥ 18 years) between April and July 2014. In total, 64.8% were aware of the existence of ancestry-based carrier screening, and respondents were generally positive about screening. About half (53.8%) preferred pan-et

SUBMITTER: Holtkamp KC 

PROVIDER: S-EPMC4717216 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature