Prognostic value of preoperative intratumoral FDG uptake heterogeneity in early stage uterine cervical cancer.

ABSTRACT:

Objective

We investigated the prognostic value of intratumoral [¹⁸F]fluorodeoxyglucose (FDG) uptake heterogeneity (IFH) derived from positron emission tomography/computed tomography (PET/CT) in patients with cervical cancer.

Methods

Patients with uterine cervical cancer of the International Federation of Obstetrics and Gynecology (FIGO) stage IB to IIA were imaged with [¹⁸F]FDG PET/CT before radical surgery. PET/CT parameters such as maximum and average standardized uptake values (SUV(max) and SUV(avg)), metabolic tumor volume (MTV), total lesion glycolysis (TLG), and IFH were assessed. Regression analyses were used to identify clinicopathological and imaging variables associated with progression-free survival (PFS).

Results

We retrospectively reviewed clinical data o

SUBMITTER: Chung HH 

PROVIDER: S-EPMC4717220 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature