The incidence and prevalence of systemic lupus erythematosus in the UK, 1999-2012.

ABSTRACT:

Objectives

To estimate the incidence and prevalence of systemic lupus erythematosus (SLE) in the UK over the period 1999-2012.

Methods

A retrospective cohort study using the Clinical Practice Research Datalink (CPRD). The incidence was calculated per 100 000 person-years and the prevalence was calculated per 100 000 people for the period 1999-2012 and stratified by year, age group, gender, region and ethnicity. Three definitions of SLE were explored: (1) systemic lupus, (2) a fully comprehensive definition of lupus including cutaneous only lupus and (3) requiring supporting evidence of SLE in the medical record.

Results

Using our primary definition of SLE, the incidence during the study period was 4.91/100 000 person-years (95% CI 4.73 to 5.09), with an annual 1.8% de

SUBMITTER: Rees F 

PROVIDER: S-EPMC4717400 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature