Quantitative Neuroimaging Software for Clinical Assessment of Hippocampal Volumes on MR Imaging.

ABSTRACT:

Background

Multiple neurological disorders including Alzheimer's disease (AD), mesial temporal sclerosis, and mild traumatic brain injury manifest with volume loss on brain MRI. Subtle volume loss is particularly seen early in AD. While prior research has demonstrated the value of this additional information from quantitative neuroimaging, very few applications have been approved for clinical use. Here we describe a US FDA cleared software program, NeuroreaderTM, for assessment of clinical hippocampal volume on brain MRI.

Objective

To present the validation of hippocampal volumetrics on a clinical software program.

Method

Subjects were drawn (n = 99) from the Alzheimer Disease Neuroimaging Initiative study. Volumetric brain MR imaging was acquired in both 1.5 T (n = 5

SUBMITTER: Ahdidan J 

PROVIDER: S-EPMC4718601 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature