Association of Serum Lipids and Coronary Heart Disease in Contemporary Observational Studies.

ABSTRACT:

Background

The use of statins increased among US adults with high coronary heart disease (CHD) risk after publication of the 2001 cholesterol treatment guidelines.

Methods and results

We analyzed the association between lipids and CHD among 9578 REasons for Geographic And Racial Differences in Stroke (REGARDS) study participants and 346,595 Kaiser Permanente Southern California (KPSC) members with baseline lipid measurements in 2003 to 2007. We performed the same analyses among 14,590 Atherosclerosis Risk In Communities (ARIC) study participants with lipid measurements in 1987 to 1989. Analyses were restricted to blacks and whites 45 to 64 years of age without CHD who were not taking statins at baseline. Total cholesterol, high-density lipoprotein cholesterol, and triglyceri

SUBMITTER: Colantonio LD 

PROVIDER: S-EPMC4718875 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature