A quantitative and qualitative review of the effects of testosterone on the function and structure of the human social-emotional brain.

ABSTRACT: Social and affective research in humans is increasingly using functional and structural neuroimaging techniques to aid the understanding of how hormones, such as testosterone, modulate a wide range of psychological processes. We conducted a meta-analysis of functional magnetic resonance imaging (fMRI) studies of testosterone administration, and of fMRI studies that measured endogenous levels of the hormone, in relation to social and affective stimuli. Furthermore, we conducted a review of structural MRI i.e. voxel based morphometry (VBM) studies which considered brain volume in relation to testosterone levels in adults and in children. In the included testosterone administration fMRI studies, which consisted of female samples only, bilateral amygdala/parahippocampal regions as well as the

SUBMITTER: Heany SJ 

PROVIDER: S-EPMC4718938 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature