Introducing MINA--The Molecularly Imprinted Nanoparticle Assay.

ABSTRACT: A new ELISA- (enzyme-linked immunosorbent assay)-like assay is demonstrated in which no elements of biological origin are used for molecular recognition or signaling. Composite imprinted nanoparticles that contain a catalytic core and which are synthesized by using a solid-phase approach can simultaneously act as recognition/signaling elements, and be used with minimal modifications to standard assay protocols. This assay provides a new route towards replacement of unstable biomolecules in immunoassays.

SUBMITTER: Shutov RV 

PROVIDER: S-EPMC4719181 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature