Genome-wide analysis of long non-coding RNAs at early stage of skin pigmentation in goats (Capra hircus).

ABSTRACT:

Background

Long noncoding RNAs (lncRNAs) play roles in almost all biological processes; however, their function and profile in skin development and pigmentation is less understood. In addition, because lncRNAs are species-specific, their function in goats has not been established.

Result

We systematically identified lncRNAs in 100-day-old fetal skin by deep RNA-sequencing using the Youzhou dark goat (dark skin) and Yudong white goat (white skin) as a model of skin pigmentation. A total of 841,895,634 clean reads were obtained from six libraries (samples). We identified 1336 specific lncRNAs in fetal skin that belonged to three subtypes, including 999 intergenic lncRNAs (lincRNAs), 218 anti-sense lncRNAs, and 119 intronic lncRNAs. Our results demonstrated significant differen

SUBMITTER: Ren H 

PROVIDER: S-EPMC4719336 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature