Ontology highlight
ABSTRACT:
SUBMITTER: Carlson-Stevermer J
PROVIDER: S-EPMC4720027 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Stem cell reports 20160101 1
CRISPR-Cas9 gene editing of human cells and tissues holds much promise to advance medicine and biology, but standard editing methods require weeks to months of reagent preparation and selection where much or all of the initial edited samples are destroyed during analysis. ArrayEdit, a simple approach utilizing surface-modified multiwell plates containing one-pot transcribed single-guide RNAs, separates thousands of edited cell populations for automated, live, high-content imaging and analysis. T ...[more]