Altered source memory retrieval is associated with pathological doubt in obsessive-compulsive disorder.

ABSTRACT: Individuals with obsessive-compulsive disorder (OCD) often complain of doubt related to memory. As neuropsychological research has demonstrated that individuals with OCD tend to focus on details and miss the larger context, the construct of source (contextual) memory may be particularly relevant to memory complaints in OCD. Memory for object versus contextual information relies on partially distinct regions within the prefrontal cortex, parietal and medial temporal lobe, and may be differentially impacted by OCD. In the present study, we sought to test the hypothesis that individuals with OCD exhibit impaired source memory retrieval using a novel memory paradigm - The Memory for Rooms Test (MFRT) - a four-room memory task in which participants walk through four rooms and attempt to encode

SUBMITTER: Olson CA 

PROVIDER: S-EPMC4720123 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature