Bioconductor's EnrichmentBrowser: seamless navigation through combined results of set- & network-based enrichment analysis.

ABSTRACT:

Background

Enrichment analysis of gene expression data is essential to find functional groups of genes whose interplay can explain experimental observations. Numerous methods have been published that either ignore (set-based) or incorporate (network-based) known interactions between genes. However, the often subtle benefits and disadvantages of the individual methods are confusing for most biological end users and there is currently no convenient way to combine methods for an enhanced result interpretation.

Results

We present the EnrichmentBrowser package as an easily applicable software that enables (1) the application of the most frequently used set-based and network-based enrichment methods, (2) their straightforward combination, and (3) a detailed and interactive visuali

SUBMITTER: Geistlinger L 

PROVIDER: S-EPMC4721010 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature