The genetic diversity and geographical separation study of Oncomelania hupensis populations in mainland China using microsatellite loci.

ABSTRACT:

Background

Oncomelania hupensis is the unique intermediate host of Schistosoma japonicum, which plays a crucial role in the transmission of schistosomiasis. The endemic area of S. japonicum is strictly consistent with the geographical distribution of O. hupensis.

Methods

A total of 24 populations of O. hupensis from four ecological landscapes were selected for analysis of genetic diversity by screening eight microsatellite DNA polymorphic loci.

Results

The number of alleles per locus ranged from 29 to 70 with an average of 45.625 and that of effective alleles were 18.5 to 45.8 with an average of 27.4. The observed (Ho) and expected (He) heterozygosities varied from 0.331 to 0.57 and from 0.888 to 0.974, respectively. The mean of polymorphism information content (PIC)

SUBMITTER: Guan W 

PROVIDER: S-EPMC4721134 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature