Exercise Mode Moderates the Relationship Between Mobility and Basal Ganglia Volume in Healthy Older Adults.

ABSTRACT:

Objectives

To examine whether 12 months of aerobic training (AT) moderated the relationship between change in mobility and change in basal ganglia volume than balance and toning (BAT) exercises in older adults.

Design

Secondary analysis of a randomized controlled trial.

Setting

Champaign-Urbana, Illinois.

Participants

Community-dwelling older adults (N=101; mean age 66.4).

Intervention

Twelve-month exercise trial with two groups: AT and BAT.

Measurements

Mobility was assessed using the Timed Up and Go test. Basal ganglia (putamen, caudate nucleus, pallidum) was segmented from T1-weighted magnetic resonance images using the Oxford Centre for Functional Magnetic Resonance Imaging of the Brain Software Library Integrated Registration and Segmentation

SUBMITTER: Nagamatsu LS 

PROVIDER: S-EPMC4721260 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature