Effects of walking on low-grade inflammation and their implications for Type 2 Diabetes.

ABSTRACT:

Objective

Inflammatory cytokines released by hypertrophic adipocytes contribute to low-grade inflammation, a characteristic of Type 2 Diabetes. Skeletal muscle contraction during physical activity stimulates the secretion of anti-inflammatory cytokines able to counteract this inflammatory status. The aim of this study was to review the evidence of the effectiveness of walking as a physical activity intervention to reduce inflammation. The interplay between adipose tissue and skeletal muscle contributions was also investigated.

Method

A structured literature review of papers available up to December 2014 was carried out within the PubMed, Scopus and ISI Web of Science databases using the keywords "walking" and "inflammation" in order to identify the studies involving healthy

SUBMITTER: Morettini M 

PROVIDER: S-EPMC4721345 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature