Nicotine replacement therapy to aid gradual cessation in smokers with no intention to quit: Association between reduction quantity and later abstinence.

ABSTRACT:

Objective

We examined how quantity and trajectory of smoking reduction influence later abstinence in smokers without intention to quit and being prescribed free nicotine replacement therapy (NRT).

Method

We conducted an a posteriori analysis from a data archive of adult smokers in a randomized controlled trial of smoking reduction using counseling and free NRT (n = 928). Reduction was analyzed as the absolute and percentage decrease in self-reported daily cigarette consumption at three follow-ups (1 week, 1 and 3 months) compared with the baseline. Logistic regression model and multiple imputation were used to examine the association between early reduction and abstinence at 6 months.

Results

Reducing 10% of cigarette consumption at the three follow-ups was associated

SUBMITTER: Cheung YT 

PROVIDER: S-EPMC4721443 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature