Ambient Temperature and Cerebrovascular Hemodynamics in the Elderly.

ABSTRACT:

Background and purpose

Some prior studies have linked ambient temperature with risk of cerebrovascular events. If causal, the pathophysiologic mechanisms underlying this putative association remain unknown. Temperature-related changes in cerebral vascular function may play a role, but this hypothesis has not been previously evaluated.

Methods

We evaluated the association between ambient temperature and cerebral vascular function among 432 participants ≥65 years old from the MOBILIZE Boston Study with data on cerebrovascular blood flow, cerebrovascular resistance, and cerebrovascular reactivity in the middle cerebral artery. We used linear regression models to assess the association of mean ambient temperature in the previous 1 to 28 days with cerebrovascular hemodynamics adj

SUBMITTER: Pan WC 

PROVIDER: S-EPMC4721538 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature