Comparisons and Limitations of Current Definitions of Bronchopulmonary Dysplasia for the Prematurity and Respiratory Outcomes Program.

ABSTRACT:

Rationale

Bronchopulmonary dysplasia is the most common morbidity of prematurity, but the validity and utility of commonly used definitions have been questioned.

Objectives

To compare three commonly used definitions of bronchopulmonary dysplasia in a contemporary prospective, multicenter observational cohort of extremely preterm infants.

Methods

At 36 weeks postmenstrual age, the following definitions of bronchopulmonary dysplasia were applied to surviving infants with and without imputation: need for supplemental oxygen (Shennan definition), National Institutes of Health Workshop definition, and "physiologic" definition after a room-air challenge.

Measurements and main results

Of 765 survivors assessed at 36 weeks, bronchopulmonary dysplasia was diagnosed in 4

SUBMITTER: Poindexter BB 

PROVIDER: S-EPMC4722827 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature