Correlation between PON1 gene polymorphisms and breast cancer risk: a Meta-analysis.

ABSTRACT:

Objective

A number of studies have investigated the relationship between the PON1 gene polymorphisms and breast cancer risk, but the conclusions are not consistent. In this paper, a meta-analysis was conducted to explore the possible reasons for these inconsistencies, expecting to further clarify the correlation between PON1 gene polymorphisms and breast cancer risk.

Methods

After searches in the database such as MEDLINE, EBSCO, ProQuest, Google Scholar, High-Wire, SID (Scientific Information Database) and PubMed, 7 literatures were collected. RevMan 5.2 software was used to perform the meta-analysis. Random-effects or fixed-effects model was used to analyze the odds ratio (OR) and 95% confidence intervals.

Results

The analysis of L55M single nucleotide polymorphisms

SUBMITTER: Wen Y 

PROVIDER: S-EPMC4723795 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature