The impact of tumor size on the association of the extent of lymph node resection and survival in clinical stage I non-small cell lung cancer.

ABSTRACT:

Introduction

Lymph node evaluation for node-negative non-small cell lung cancer (NSCLC) is associated with long-term survival but it is not clear if smaller tumors require as extensive a pathologic nodal assessment as larger tumors. This study evaluated the relationship of tumor size and optimal extent of lymph node resection using the National Cancer Data Base (NCDB).

Materials and methods

The incremental survival benefit of each additional lymph node that was evaluated for patients in the NCDB who underwent lobectomy for clinical Stage I NSCLC from 2003 to 2006 was evaluated using Cox multivariable proportional hazards regression modeling. The impact of tumor size was assessed by repeating the Cox analysis with patients stratified by tumor size ≥2 cm vs <2 cm.

Results</

SUBMITTER: Gulack BC 

PROVIDER: S-EPMC4724282 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature