Early Childhood Behavioral Inhibition Predicts Cortical Thickness in Adulthood.

ABSTRACT:

Objective

Behavioral inhibition (BI) during early childhood predicts risk for anxiety disorders and altered cognitive control in adolescence. Although BI has been linked to variation in brain function through adulthood, few studies have examined relations between early childhood BI and adult brain structure.

Method

The relation between early childhood BI and cortical thickness in adulthood was examined in a cohort of individuals followed since early childhood (N = 53, mean age 20.5 years). Analyses tested whether anxiety and/or cognitive control during adolescence moderated relations between BI and cortical thickness. Cognitive control was measured with the Eriksen Flanker Task. Initial analyses examined cortical thickness in regions of interest previously implicated in BI,

SUBMITTER: Sylvester CM 

PROVIDER: S-EPMC4724382 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature