Association between Antiplatelet or Anticoagulant Drugs and Retinal or Subretinal Hemorrhage in the Comparison of Age-Related Macular Degeneration Treatments Trials.

ABSTRACT:

Purpose

To evaluate the association between use of antiplatelet or anticoagulant drugs and retinal or subretinal hemorrhage in participants with neovascular age-related macular degeneration (AMD) in the Comparison of AMD Treatments Trials (CATT).

Design

Cohort study within CATT.

Participants

Participants in CATT with untreated active neovascular AMD (n = 1185).

Methods

Participants were interviewed for use of antiplatelet or anticoagulant drugs. Trained readers evaluated photographs for the presence and size of retinal or subretinal hemorrhage at baseline and years 1 and 2. Associations between use of antiplatelet or anticoagulant drugs and hemorrhage were evaluated among all participants and by baseline hypertension status using multivariate logistic regressio

SUBMITTER: Ying GS 

PROVIDER: S-EPMC4724480 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature