Phylogenomic analysis reveals genome-wide purifying selection on TBE transposons in the ciliate Oxytricha.

ABSTRACT:

Background

Transposable elements are a major player contributing to genetic variation and shaping genome evolution. Multiple independent transposon domestication events have occurred in ciliates, recruiting transposases to key roles in cellular processes. In the ciliate Oxytricha trifallax, the telomere-bearing elements (TBE), a Tc1/mariner transposon, occupy a significant portion of the germline genome and are involved in programmed genome rearrangements that produce a transcriptionally active somatic nucleus from a copy of the germline nucleus during development.

Results

Here we provide a thorough characterization of the distribution and sequences of TBE transposons in the Oxytricha germline genome. We annotate more than 10,000 complete and 24,000 partial TBE sequences. TB

SUBMITTER: Chen X 

PROVIDER: S-EPMC4724952 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature