Assessment and prevalence of pulmonary oedema in contemporary acute heart failure trials: a systematic review.

ABSTRACT:

Aims

Pulmonary oedema is a common and important finding in acute heart failure (AHF). We conducted a systematic review to describe the methods used to assess pulmonary oedema in recent randomized AHF trials and report its prevalence in these trials.

Methods and results

Of 23 AHF trials published between 2002 and 2013, six were excluded because they were very small or not randomized, or missing full-length publications. Of the remaining 17 (n = 200-7141) trials, six enrolled patients with HF and reduced ejection fraction (HF-REF) and 11, patients with both HF-REF and HF with preserved ejection fraction (HF-PEF). Pulmonary oedema was an essential inclusion criterion, in most trials, based upon findings on physical examination ('rales'), radiographic criteria ('signs of congest

SUBMITTER: Platz E 

PROVIDER: S-EPMC4725064 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature