Microbial community profiling shows dysbiosis in the lesional skin of Vitiligo subjects.

ABSTRACT: Healthy human skin harbours a diverse array of microbes that comprise the skin microbiome. Commensal bacteria constitute an important component of resident microbiome and are intricately linked to skin health. Recent studies describe an association between altered skin microbial community and epidemiology of diseases, like psoriasis, atopic dermatitis etc. In this study, we compare the differences in bacterial community of lesional and non-lesional skin of vitiligo subjects. Our study reveals dysbiosis in the diversity of microbial community structure in lesional skin of vitiligo subjects. Although individual specific signature is dominant over the vitiligo-specific microbiota, a clear decrease in taxonomic richness and evenness can be noted in lesional patches. Investigation of community

SUBMITTER: Ganju P 

PROVIDER: S-EPMC4725359 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature