Ontology highlight
ABSTRACT:
SUBMITTER: Das M
PROVIDER: S-EPMC4726462 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
PloS one 20160125 1
In this study, we conducted an epigenome-wide association study of metabolic syndrome (MetS) among 846 participants of European descent in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). DNA was isolated from CD4+ T cells and methylation at ~470,000 cytosine-phosphate-guanine dinucleotide (CpG) pairs was assayed using the Illumina Infinium HumanMethylation450 BeadChip. We modeled the percentage methylation at individual CpGs as a function of MetS using linear mixed models. A Bonfe ...[more]