A Voxel-Based Morphometric MRI Study in Young Adults with Borderline Personality Disorder.

ABSTRACT:

Background

Increasing evidence has documented subtle changes in brain morphology and function in patients with borderline personality disorder (BPD). However, results of magnetic resonance imaging volumetry in patients with BPD are inconsistent. In addition, few researchers using voxel-based morphometry (VBM) have focused on attachment and childhood trauma in BPD. This preliminary study was performed to investigate structural brain changes and their relationships to attachment and childhood trauma in a homogenous sample of young adults with BPD.

Method

We examined 34 young adults with BPD and 34 healthy controls (HCs) to assess regionally specific differences in gray matter volume (GMV) and gray matter concentration (GMC). Multiple regressions between brain volumes measured

SUBMITTER: Jin X 

PROVIDER: S-EPMC4726531 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature