Osmolality of Cerebrospinal Fluid from Patients with Idiopathic Intracranial Hypertension (IIH).

ABSTRACT:

Introduction

Idiopathic intracranial hypertension (IIH) is a disorder of increased intracranial fluid pressure (ICP) of unknown etiology. This study aims to investigate osmolality of cerebrospinal fluid (CSF) from patients with IIH.

Methods

We prospectively collected CSF from individuals referred on suspicion of IIH from 2011-2013. Subjects included as patients fulfilled Friedman and Jacobson's diagnostic criteria for IIH. Individuals in whom intracranial hypertension was refuted were included as controls. Lumbar puncture with ICP measurement was performed at inclusion and repeated for patients after three months of treatment. Osmolality was measured with a Vapor Pressure Osmometer.

Results

We collected 90 CSF samples from 38 newly diagnosed patients and 28 controls.

SUBMITTER: Wibroe EA 

PROVIDER: S-EPMC4726547 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature