Neurophysiological biomarkers for Lewy body dementias.

ABSTRACT:

Objective

Lewy body dementias (LBD) include both dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD), and the differentiation of LBD from other neurodegenerative dementias can be difficult. Currently, there are few biomarkers which might assist early diagnosis, map onto LBD symptom severity, and provide metrics of treatment response. Traditionally, biomarkers in LBD have focussed on neuroimaging modalities; however, as biomarkers need to be simple, inexpensive and non-invasive, neurophysiological approaches might also be useful as LBD biomarkers.

Methods

In this review, we searched PubMED and PsycINFO databases in a semi-systematic manner in order to identify potential neurophysiological biomarkers in the LBDs.

Results

We identified 1491 studie

SUBMITTER: Cromarty RA 

PROVIDER: S-EPMC4727506 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature