New Drugs from Marine Organisms in Alzheimer's Disease.

ABSTRACT: Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder. Current approved drugs may only ameliorate symptoms in a restricted number of patients and for a restricted period of time. Currently, there is a translational research challenge into identifying the new effective drugs and their respective new therapeutic targets in AD and other neurodegenerative disorders. In this review, selected examples of marine-derived compounds in neurodegeneration, specifically in AD field are reported. The emphasis has been done on compounds and their possible relevant biological activities. The proposed drug development paradigm and current hypotheses should be accurately investigated in the future of AD therapy directions although taking into account successful examples of such approach re

SUBMITTER: Russo P 

PROVIDER: S-EPMC4728502 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature