Ontology highlight
ABSTRACT:
SUBMITTER: Wang G
PROVIDER: S-EPMC4728534 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Toxins 20151230 1
Several species of the genus Veratrum that produce steroid alkaloids are commonly used to treat pain and hypertension in China and Europe. However, Veratrum alkaloids (VAs) induce serious cardiovascular toxicity. In China, Veratrum treatment often leads to many side effects and even causes the death of patients, but the pathophysiological mechanisms under these adverse effects are not clear. Here, two solanidine-type VAs (isorubijervine and rubijervine) isolated from Veratrum taliense exhibited ...[more]