Smartphone-Based Fluorescent Diagnostic System for Highly Pathogenic H5N1 Viruses.

ABSTRACT: Field diagnostic tools for avian influenza (AI) are indispensable for the prevention and controlled management of highly pathogenic AI-related diseases. More accurate, faster and networked on-site monitoring is demanded to detect such AI viruses with high sensitivity as well as to maintain up-to-date information about their geographical transmission. In this work, we assessed the clinical and field-level performance of a smartphone-based fluorescent diagnostic device with an efficient reflective light collection module using a coumarin-derived dendrimer-based fluorescent lateral flow immunoassay. By application of an optimized bioconjugate, a smartphone-based diagnostic device had a two-fold higher detectability as compared to that of the table-top fluorescence strip reader for three diffe

SUBMITTER: Yeo SJ 

PROVIDER: S-EPMC4729771 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature