Clinicopathological significance of NGX6 expression in breast cancer and its relationship to angiogenesis.

ABSTRACT:

Objective

The aim was to explore clinicopathological significance of Nasopharyngeal carcinoma-associated gene 6 (NGX6) expression in breast cancer and its relationship to angiogenesis.

Methods

Clinicopathological feature of 168 patients with breast cancer were analyzed. NGX6 expression and microvessel density (MVD) in tumor tissue were measured using immunohistochemistry methods. The association of NGX6 expression with MVD and clinicopathological features was assessed.

Results

Among 168 cases of breast cancer, NGX6 positive expression were found in 92 (54.8%) cases and NGX6 negative expression were found in 76 (45.2%) cases. Incidence rate of large size tumor, high tumor node metastasis (TNM) stage and lymph node metastasis in NGX6 negative expression group were highe

SUBMITTER: Xiao J 

PROVIDER: S-EPMC4729981 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature