Identification of molecular signatures specific for distinct cranial sensory ganglia in the developing chick.

ABSTRACT:

Background

The cranial sensory ganglia represent populations of neurons with distinct functions, or sensory modalities. The production of individual ganglia from distinct neurogenic placodes with different developmental pathways provides a powerful model to investigate the acquisition of specific sensory modalities. To date there is a limited range of gene markers available to examine the molecular pathways underlying this process.

Results

Transcriptional profiles were generated for populations of differentiated neurons purified from distinct cranial sensory ganglia using microdissection in embryonic chicken followed by FAC-sorting and RNAseq. Whole transcriptome analysis confirmed the division into somato- versus viscerosensory neurons, with additional evidence for subdivis

SUBMITTER: Patthey C 

PROVIDER: S-EPMC4730756 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature