Intravoxel Incoherent Motion MR Imaging for Staging of Hepatic Fibrosis.

ABSTRACT:

Objectives

To determine the potential of intravoxel incoherent motion (IVIM) MR imaging for staging of hepatic fibrosis (HF).

Methods

We searched PubMed and EMBASE from their inception to 31 July 2015 to select studies reporting IVIM MR imaging and HF staging. We defined F1-2 as non-advanced HF, F3-4 as advanced HF, F0 as normal liver, F1 as very early HF, and F2-4 as significant HF. Then we compared stage F0 with F1, F0-1 with F2-3, and F1-2 with F3-4 using IVIM-derived parameters (pseudo-diffusion coefficient D*, perfusion fraction f, and pure molecular diffusion parameter D). The effect estimate was expressed as a pooled weighted mean difference (WMD) with 95% confidence interval (CI), using the fixed-effects model.

Results

Overall, we included six papers (406 pati

SUBMITTER: Zhang B 

PROVIDER: S-EPMC4731200 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature