Adiposity trajectory and its associations with plasma adipokine levels in children and adolescents-A prospective cohort study.

ABSTRACT:

Objective

This study aimed to examine the associations of longitudinal adiposity measures with two adipokines, leptin and adiponectin, and their ratio in children and adolescents.

Methods

A total of 953 children and adolescents participated in a 6-year longitudinal study. Body mass index (BMI), percentage body fat (%BF), and fat mass index (FMI) were used to assess adiposity status.

Results

After adjusting for possible confounders, our regression models revealed that BMI, %BF, and FMI, in both the baseline and follow-up surveys were independently associated with a higher level of leptin and the leptin/adiponectin ratio at the follow-up survey, whereas the significant association with adiponectin only partly existed in adiposity measures at the follow-up visit. Moreove

SUBMITTER: Li S 

PROVIDER: S-EPMC4731239 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature