Lewis Acid Mediated Vinylogous Additions of Enol Nucleophiles into an α,β-Unsaturated Platinum Carbene.

ABSTRACT: A variety of substituted indoles and benzofurans are accessed via a platinum catalyzed annulation and vinylogous addition of enol nucleophiles. Several β-dicarbonyl compounds participate in the reaction, as do α-nitro and α-cyano carbonyl species. Subjecting the indole products to acidic conditions results in the formation of fused heterocycles.

SUBMITTER: Allegretti PA 

PROVIDER: S-EPMC4732870 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature