Early prognostication markers in cardiac arrest patients treated with hypothermia.

ABSTRACT:

Background and purpose

Established prognostication markers, such as clinical findings, electroencephalography (EEG) and biochemical markers, used by clinicians to predict neurological outcome after cardiac arrest (CA) are altered under therapeutic hypothermia (TH) conditions and their validity remains uncertain.

Methods

MEDLINE and Embase were searched for evidence on the current standards for neurological outcome prediction for out-of-hospital CA patients treated with TH and the validity of a wide range of prognostication markers. Relevant studies that suggested one or several established biomarkers and multimodal approaches for prognostication are included and reviewed.

Results

Whilst the prognostic accuracy of various tests after TH has been questioned, pupillary l

SUBMITTER: Karapetkova M 

PROVIDER: S-EPMC4733576 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature