Identification of Conserved and Potentially Regulatory Small RNAs in Heterocystous Cyanobacteria.

ABSTRACT: Small RNAs (sRNAs) are a growing class of non-protein-coding transcripts that participate in the regulation of virtually every aspect of bacterial physiology. Heterocystous cyanobacteria are a group of photosynthetic organisms that exhibit multicellular behavior and developmental alternatives involving specific transcriptomes exclusive of a given physiological condition or even a cell type. In the context of our ongoing effort to understand developmental decisions in these organisms we have undertaken an approach to the global identification of sRNAs. Using differential RNA-Seq we have previously identified transcriptional start sites for the model heterocystous cyanobacterium Nostoc sp. PCC 7120. Here we combine this dataset with a prediction of Rho-independent transcriptional terminators

SUBMITTER: Brenes-Alvarez M 

PROVIDER: S-EPMC4734099 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature