The prognostic importance of weight loss in coronary artery disease: a systematic review and meta-analysis.

ABSTRACT:

Objective

To assess the prognostic impact of weight loss on clinical outcomes in patients with coronary artery disease (CAD).

Methods

We performed a systematic review and meta-analysis of the prognostic effects of weight loss in patients with CAD on a composite outcome of all-cause mortality, cardiovascular mortality, and major adverse cardiac events considering studies published between January 1, 1964, and August 8, 2013. We considered weight loss "intentional" when it occurred in the presence of programmed therapeutic lifestyle changes and "observational" when no such intervention was specified.

Results

We searched 1218 abstracts, of which 12 studies with 14 cohorts met the inclusion criteria. A total of 35,335 patients (mean age, 64 years; 72% male; body mass inde

SUBMITTER: Pack QR 

PROVIDER: S-EPMC4734114 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature