The severity of the metabolic syndrome increases over time within individuals, independent of baseline metabolic syndrome status and medication use: The Atherosclerosis Risk in Communities Study.

ABSTRACT:

Background and aims

The severity of the metabolic syndrome (MetS) is linked to future cardiovascular disease. However, it is unclear whether MetS severity increases among individuals followed over time.

Methods

We assessed changes in a sex- and race/ethnicity-specific MetS severity Z-score over a 10-year period (visits 1-4) among 9291 participants of the Atherosclerosis Risk in Communities study cohort. We compared sex- and racial/ethnic subgroups for the rate of change in the MetS severity score and MetS prevalence as assessed using traditional ATP-III MetS criteria. We further examined effects of use of medications for hypertension, diabetes and dyslipidemia.

Results

Over the 10 years of follow-up, MetS severity Z-scores increased in 76% of participants from an over

SUBMITTER: Vishnu A 

PROVIDER: S-EPMC4734118 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature