Association between the expression levels of TAZ, AXL and CTGF and clinicopathological parameters in patients with colon cancer.

ABSTRACT: Colon cancer accounts for a large proportion of all the cancer-associated morbidities worldwide. Genetic analysis and stratification of patients based on survival may identify genetic signatures potentially useful for prognostic or treatment planning purposes. Previous studies have reported that the messenger (m)RNA expression levels of tafazzin (TAZ), AXL receptor tyrosine kinase (AXL) and connective tissue growth factor (CTGF) were able to predict the survival of patients with colon cancer in two independent colon cancer datasets. However, limited clinicopathological data were available from these two datasets. By contrast, a large colon cancer dataset comprising 566 patients has been recently published in the Gene Expression Omnibus database, which contains data regarding tumor stage an

SUBMITTER: Zhang SD 

PROVIDER: S-EPMC4734239 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature