Current therapeutic strategies for advanced pancreatic cancer: A review for clinicians.

ABSTRACT: Pancreatic cancer (PC) would become the second leading cause of cancer death in the near future, despite representing only 3% of new cancer diagnosis. Survival improvement will come from a better knowledge of risk factors, earlier diagnosis, better integration of locoregional and systemic therapies, as well as the development of more efficacious drugs rising from a deeper understanding of disease biology. For patients with unresectable, non-metastatic disease, combined strategies encompassing primary chemotherapy and radiation seems to be promising. In fit patients, new polychemotherapy regimens can lead to better outcomes in terms of slight but significant survival improvement associated with a positive impact on quality of life. The upfront use of these regimes can also increase the rate

SUBMITTER: Spadi R 

PROVIDER: S-EPMC4734936 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature