Role of Helicobacter pylori and interleukin 6 -174 gene polymorphism in dyslipidemia: a case-control study.

ABSTRACT:

Objective

To assess the role of Helicobacter pylori infection and interleukin 6 polymorphism -174 (rs1800795) in dyslipidemia.

Design

Case-control study comparing serum lipids between H. pylori positive and negative patients and controlling for IL-6 -174 polymorphism, age, sex and smoking.

Setting

3 hospitals performing outpatient endoscopies in the city of Oulu, Finland.

Participants

199 adult patients with dyspepsia symptoms fulfilling Rome criteria originating from ethnically Finnish population. Patients with an immunosuppressive disorder or malignant disease, treated H. pylori infection, immunosuppressive or anticoagulant medication, previous gastric surgery or ongoing antibiotic treatment were excluded.

Primary outcome measures

Association of H. pyl

SUBMITTER: Pohjanen VM 

PROVIDER: S-EPMC4735314 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature