An integrated multi-electrode-optrode array for in vitro optogenetics.

ABSTRACT: Modulation of a group of cells or tissue needs to be very precise in order to exercise effective control over the cell population under investigation. Optogenetic tools have already demonstrated to be of great value in the study of neuronal circuits and in neuromodulation. Ideally, they should permit very accurate resolution, preferably down to the single cell level. Further, to address a spatially distributed sample, independently addressable multiple optical outputs should be present. In current techniques, at least one of these requirements is not fulfilled. In addition to this, it is interesting to directly monitor feedback of the modulation by electrical registration of the activity of the stimulated cells. Here, we present the fabrication and characterization of a fully integrated si

SUBMITTER: Welkenhuysen M 

PROVIDER: S-EPMC4735812 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature