Design of the PROUD study: PCR faeces testing in outpatients with diarrhoea.

ABSTRACT:

Background

Infectious intestinal disease (IID) is an important cause of morbidity in developed countries and a frequent reason for general practitioner (GP) consultation. In recent years polymerase chain reaction (PCR) based techniques have gradually replaced conventional enteropathogen detection techniques like microscopy and culture in primary care patients suspected of IID. PCR features testing of multiple enteropathogens in a single faecal sample with shorter turnaround times and greater sensitivity compared to conventional techniques. However, the associated costs and benefits have not been quantified. Furthermore, primary care incidence and prevalence estimates of enteropathogens associated with IID are sparsely available and predominantly based on conventional techniques. Th

SUBMITTER: Schierenberg A 

PROVIDER: S-EPMC4736251 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature